well, checked anyway for you.
closist I found:
http://forums.msexchange.org/ultimatebb.cgi?ubb=get_topic;f=3;t=001882

so, if the client has profile created before destroy/overwrite it if you have upgraded your server.

other one I recall from memory:
if you have no exchange mailbox (as many administrative accounts do not) it will produce an error if trying to create a profile.

cheers,
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