Works for me as well. In fact here is an example of part of script that modifies remote production workstations that don't have keyboards or mice on them.

I use the following from an elevated command prompt to enable remote registry (which is off by default on Windows 7) - could do with KiX if you wanted as well but command line was just as fast for me in this case.

sc \\COMP02-CS01 config RemoteRegistry start= auto
sc \\COMP02-CS01 start RemoteRegistry



 Code:
$SO=SetOption('Explicit','On')
$SO=SetOption('NoVarsInStrings','On')
$SO=SetOption('WrapAtEOL','On')
$SO=SETOPTION('WOW64AlternateRegView','on')

Dim $Update, $sComputer, $Key, $Value, $Data, $DataType

$sComputer='COMP02-CS01'
$Key = 'HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Internet Explorer\MAIN'
$Value = 'Default_Page_URL'
$Data = 'http://handcode-app/viewer/default.aspx?l=19&s=3'
$DataType = 'REG_SZ'

$sComputer=IIf(Not $sComputer,'','\\'+Join(Split($sComputer,'\'),'',3)+'\')
$Update=WriteValue($sComputer+$Key,$Value,$Data,$DataType)