Sure it's possible, but why would you?

I hope you manage a small number of users - I would not want to be in your shoes when multiple application installs run during login for multiple users!

This also assumes that your users are local admins.. bad design.

You could create a self-service web portal pretty easily with some ASP code.. when a user clicks on "Install Skype", the back-end process drops the request into a folder where a kix script pushes the install command to the user. A bit more complex, but much more controlled and secure.

Glenn
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Actually I am a Rocket Scientist! \:D