If you are using the Vault script, you can use one template for UK and one for International, and just put the prefix in the template..

We've deployed the v1.7 release to a company with 6 templates and about 30 unique signature configurations, based on OU or AD Group. No changes to coding or anything. The 6 templates represent 5 different divisions within the company, plus a unique template for management.

Glenn
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Actually I am a Rocket Scientist! \:D