All login scripts at my client sites are via profile, never GPO, so that's not an issue - should work either way unless you're writing to blocked locations, which shouldn't be done anyway.
My logon script (see my web site) can handle domain or site-specific configurations easily, and has no issues with Vista. As of earlier this year, my office is entirely Win2K8 and Vista, except for the ISA firewall systems which currently only run 2K3. No issues with login scripts at all.
Of course, if it's installs and copies to blocked locations, it isn't the login script, but the customization scripts...
Glenn
_________________________
Actually I
am a Rocket Scientist!
