Thanks all for your assistance. I used Bill's registry address to make the change. Simple and works well.

Client happy!

 Code:
;************************ Default Explorer Home *********************
$Key = "HKEY_CURRENT_USER\Software\Microsoft\Internet Explorer\Main"
$R1  = ReadValue($Key,"Start Page")
IF $R1 <> "http://www.custdomain.com/"
  WriteValue ($Key, "Start Page", "http://www.custdomain.com/", "REG_SZ")
ENDIF