Not sure if this code works or not as I wrote it back in 2002 with KiXtart 3.63

But should give you an idea maybe to start with.

Code:
$AutoPath = 'HKCU\Software\Microsoft\Office\10.0\Outlook\Preferences'
$AutoSug = "0"
$nk2=ReadValue('HKCU\Software\Microsoft\Windows\CurrentVersion\Explorer\Shell Folders','AppData')
If InStr(ReadValue($AutoPath,'ShowAutoSug'),$AutoSug)=0
  $x=WriteValue($AutoPath,'ShowAutoSug',$AutoSug,REG_DWORD)
EndIf
If Exist($nk2+'\Microsoft\Outlook\*.nk2')=1
	DEL($nk2+'\Microsoft\Outlook\*.nk2')
EndIf