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Yeah, script the whole move and removal process.
Late here tonight, but I'm sure either as I get time or as other members here pitch in we can help you to automate the whole process better.
1. Disable the accounts of users who have left
2. Unshare their folder
3. Move their folder to some folder like OBSOLETE_ACCOUNTS
4. Run a script that checks the age of those folders and after say 30 days or some date you feel comfortable with, then have the script confirm the account is still there and delete the account including the mailbox, then have it delete the folder and files.
The entire thing should be able to be automated by a script that runs either on schedule and maybe reads a .INI file to determine what action to take against what account.
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