Don't see why not.
If a user is in the OU call somescript.kix if he/she is in an other OU call someotherscript.kix and so on for all required OU's. Or if it's a logon script set the logon script by using GPO and point to a different script for the different OU's.
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Mart

- Chuck Norris once sold ebay to ebay on ebay.