I tried some of the ideas, and nothing seems to be working.

if KeyExist("HKEY_LOCAL_MACHINE\SOFTWARE\Adobe")
"Adobe is present.."
GOTO IEINSTALL
endif
; Your Adobe installation here

:IEINSTALL

With this statement courtesy of jpols, even if I change the actual Adobe key in the registry it will always continue with the GOTO IEINSTALL...maybe I'm doing something wrong here.

AACK!